Structure of PDB 5th2 Chain B Binding Site BS01

Receptor Information

>5th2 Chain B (length=216) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

QVQLKQSGPGLVQPSQSLSITCTVSGFSLTNYGVHWVRQSPGKGLEWLGV
IWSGGNTDYNTPFTSRLSINKDNSKSQVFFKMNSLQSNDTAIYYCARALT
YYDYEFAYWGQGTLVTVSAASTKGPSVFPLAPSGGTAALGCLVKDYFPEP
VTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVN
HKPSNTKVDKRVEPKS

Ligand information

>5th2 Chain E (length=12) Species: 32630 (synthetic construct) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

CQFDQSTRRLKC

Receptor-Ligand Complex Structure

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Structure summary

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PDB	5th2 Natural and non-natural amino-acid side-chain substitutions: affinity and diffraction studies of meditope-Fab complexes.
Resolution	1.84 Å
Binding residue (original residue number in PDB)	Q39 P41 Q111 L114 E154 P173
Binding residue (residue number reindexed from 1)	Q39 P41 Q111 L114 E149 P168

External links

PDB	RCSB:5th2, PDBe:5th2, PDBj:5th2
PDBsum	5th2
PubMed	27834791

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