Structure of PDB 5tb5 Chain B Binding Site BS01
Receptor Information
>5tb5 Chain B (length=150) Species:
9606
(Homo sapiens) [
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MSAKDERAREILRGFKLNWMNLRDAETGKILWQGTEDLSVPGVEHEARVP
KKILKCKAVSRELNFSSTEQMEKFRLEQKVYFKGQCLEEWFFEFGFVIPN
STNTWQSLIEAAPESQMMPASVLTGNVIIETKFFDDDLLVSTSRVRLFYV
Ligand information
Ligand ID
FAR
InChI
InChI=1S/C15H26/c1-6-14(4)10-8-12-15(5)11-7-9-13(2)3/h6,9,12H,7-8,10-11H2,1-5H3/b14-6+,15-12+
InChIKey
JXBSHSBNOVLGHF-BUJBXKITSA-N
SMILES
Software
SMILES
CACTVS 3.341
OpenEye OEToolkits 1.5.0
CC=C(C)CCC=C(C)CCC=C(C)C
OpenEye OEToolkits 1.5.0
C\C=C(/C)\CC\C=C(/C)\CCC=C(C)C
CACTVS 3.341
C\C=C(C)\CC\C=C(C)\CCC=C(C)C
ACDLabs 10.04
C(=C/C)(\CC/C=C(/CC/C=C(\C)C)C)C
Formula
C15 H26
Name
FARNESYL
ChEMBL
DrugBank
ZINC
PDB chain
5tb5 Chain A Residue 201 [
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Receptor-Ligand Complex Structure
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PDB
5tb5
Structural basis of recognition of farnesylated and methylated KRAS4b by PDE delta.
Resolution
2.0 Å
Binding residue
(original residue number in PDB)
M20 S39 L63 Q78 F133
Binding residue
(residue number reindexed from 1)
M20 S39 L63 Q78 F133
Annotation score
1
Enzymatic activity
Enzyme Commision number
?
Gene Ontology
Molecular Function
GO:0005095
GTPase inhibitor activity
GO:0005515
protein binding
GO:0031267
small GTPase binding
Biological Process
GO:0007601
visual perception
GO:0050953
sensory perception of light stimulus
Cellular Component
GO:0005737
cytoplasm
GO:0005829
cytosol
GO:0005856
cytoskeleton
GO:0005929
cilium
GO:0016020
membrane
GO:0030659
cytoplasmic vesicle membrane
GO:0031410
cytoplasmic vesicle
GO:0042995
cell projection
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Molecular Function
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Biological Process
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Cellular Component
External links
PDB
RCSB:5tb5
,
PDBe:5tb5
,
PDBj:5tb5
PDBsum
5tb5
PubMed
27791178
UniProt
O43924
|PDE6D_HUMAN Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta (Gene Name=PDE6D)
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