Structure of PDB 5o6e Chain B Binding Site BS01

Receptor Information
>5o6e Chain B (length=513) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GLSKEQESIIKLAENGHNIFYTGSAGTGKSILLREMIKVLKGIYGRENVA
VTASTGLAACNIGGITIHSFAGIGLGKGDADKLYKKVRRSRKHLRRWENI
GALVVDEISMLDAELLDKLDFIARKIRKNHQPFGGIQLIFCGDFFQLPPV
SKDPNRPTKFAFESKAWKEGVKMTIMLQKVFRQRGDVKFIDMLNRMRLGN
IDDETEREFKKLSRPLPDDEIIPAELYSTRMEVERANNSRLSKLPGQVHI
FNAIDGGALEDEELKERLLQNFLAPKELHLKVGAQVMMVKNLDATLVNGS
LGKVIEFMDPETYFCYEALTNDPSMPPEKLETWAENPSKLKAAMEREQKS
SVKEGFAKSDIGEPVSPLDSSVFDFMKRVVVLENIKRKEQLMQTIHQNSA
GKRRLPLVRFKASDMSTRMVLVEPEDWAIEDENEKPLVSRVQLPLMLAWS
LSIHKSQGQTLPKVKVDLRRVFEKGQAYVALSRAVSREGLQVLNFDRTRI
KAHQKVIDFYLTL
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5o6e Insights into the structural and mechanistic basis of multifunctional S. cerevisiae Pif1p helicase.
Resolution3.345 Å
Binding residue
(original residue number in PDB)		T290 G291 T301 L310 K312 V385 K387 T464 R465 N506 F507 K525 S703 F723
Binding residue
(residue number reindexed from 1)		T55 G56 T66 L75 K77 V150 K152 T229 R230 N271 F272 K290 S452 F472
Enzymatic activity
Enzyme Commision number 3.6.4.12: DNA helicase.
Gene Ontology
Molecular Function
GO:0003678 DNA helicase activity
Biological Process
GO:0000723 telomere maintenance
GO:0006281 DNA repair

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Molecular Function
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Biological Process
External links
PDB RCSB:5o6e, PDBe:5o6e, PDBj:5o6e
PDBsum5o6e
PubMed29202194
UniProtP07271|PIF1_YEAST ATP-dependent DNA helicase PIF1 (Gene Name=PIF1)

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