Structure of PDB 5nus Chain B Binding Site BS01

Receptor Information
>5nus Chain B (length=74) Species: 759272 (Thermochaetoides thermophila DSM 1495) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
FPLKGWVEVSWAEARKSKQVGCFACLAPFPSNGNGSESGRYKCPTCGKHF
CIDCDVFAHEVIHNCPGCQADMRP
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain5nus Chain B Residue 601 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB5nus The intricate network between the p34 and p44 subunits is central to the activity of the transcription/DNA repair factor TFIIH.
Resolution2.2 Å
Binding residue
(original residue number in PDB)		C401 C404 C484 C487
Binding residue
(residue number reindexed from 1)		C22 C25 C51 C54
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0008270 zinc ion binding
Biological Process
GO:0006281 DNA repair
GO:0006289 nucleotide-excision repair
GO:0006351 DNA-templated transcription
Cellular Component
GO:0000439 transcription factor TFIIH core complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5nus, PDBe:5nus, PDBj:5nus
PDBsum5nus
PubMed28977422
UniProtG0RZE6

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