Structure of PDB 5nnc Chain B Binding Site BS01
Receptor Information
>5nnc Chain B (length=125) Species:
9606
(Homo sapiens) [
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SMNPPPPETSNPNKPKRQTNQLQYLLRVVLKTLWKHQFAWPFQQPVDAVK
LNLPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNK
PGDDIVLMAEALEKLFLQKINELPT
Ligand information
>5nnc Chain D (length=8) Species:
9606
(Homo sapiens) [
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KSTGGKAP
Receptor-Ligand Complex Structure
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PDB
5nnc
Interactome Rewiring Following Pharmacological Targeting of BET Bromodomains.
Resolution
2.22 Å
Binding residue
(original residue number in PDB)
W81 V87 N140 D144 I146
Binding residue
(residue number reindexed from 1)
W40 V46 N99 D103 I105
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:5nnc
,
PDBe:5nnc
,
PDBj:5nnc
PDBsum
5nnc
PubMed
30554943
UniProt
O60885
|BRD4_HUMAN Bromodomain-containing protein 4 (Gene Name=BRD4)
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