Structure of PDB 5nnc Chain B Binding Site BS01

Receptor Information
>5nnc Chain B (length=125) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SMNPPPPETSNPNKPKRQTNQLQYLLRVVLKTLWKHQFAWPFQQPVDAVK
LNLPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNK
PGDDIVLMAEALEKLFLQKINELPT
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5nnc Interactome Rewiring Following Pharmacological Targeting of BET Bromodomains.
Resolution2.22 Å
Binding residue
(original residue number in PDB)
W81 V87 N140 D144 I146
Binding residue
(residue number reindexed from 1)
W40 V46 N99 D103 I105
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:5nnc, PDBe:5nnc, PDBj:5nnc
PDBsum5nnc
PubMed30554943
UniProtO60885|BRD4_HUMAN Bromodomain-containing protein 4 (Gene Name=BRD4)

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