Structure of PDB 5nmp Chain B Binding Site BS01

Receptor Information
>5nmp Chain B (length=260) Species: 267608 (Ralstonia pseudosolanacearum GMI1000) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TTPTILPALAAGLARGNIRVVDLTQTLSPSFPTLQLPSQFGQVQPFKIER
ISHYDASGPAWYWNNFSCGEHTGTHFDAPAHWITGRDYPGNSVDTIAPEN
FVAPAVVIDASAQVRENEDWLLTVDFLQAWEQRHGRIPAGAWVLFRTDWS
LRVGDAAAFLNIREDGAHTPGPTQEAVEWLIGERNVHGFGVETINTDAGQ
SYAWPLAYPCHTLMHGANRYGLQCLKNLDQLPPRGAFILAAPLKIEGGSG
SPLRVLALVE
Ligand information
Ligand IDMN
InChIInChI=1S/Mn/q+2
InChIKeyWAEMQWOKJMHJLA-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mn+2]
CACTVS 3.341[Mn++]
FormulaMn
NameMANGANESE (II) ION
ChEMBL
DrugBankDB06757
ZINC
PDB chain5nmp Chain B Residue 301 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB5nmp A fundamental catalytic difference between zinc and manganese dependent enzymes revealed in a bacterial isatin hydrolase.
Resolution2.65 Å
Binding residue
(original residue number in PDB)		H74 H78 D80 Q226
Binding residue
(residue number reindexed from 1)		H71 H75 D77 Q223
Annotation score1
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0004061 arylformamidase activity
GO:0046872 metal ion binding
Biological Process
GO:0019441 tryptophan catabolic process to kynurenine

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Molecular Function
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Biological Process
External links
PDB RCSB:5nmp, PDBe:5nmp, PDBj:5nmp
PDBsum5nmp
PubMed30166577
UniProtQ8XYC3

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