Structure of PDB 5njj Chain B Binding Site BS01
Receptor Information
>5njj Chain B (length=139) Species:
9606
(Homo sapiens) [
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TDEEGVRTGKCSFPVKYLGHVEVDESRGMHICEDAVKRLKAERKFFKGFF
GKKAVKAVLWVSADGLRVVDEKTKDLIVDQTIEKVSFCAPDRNFDRAFSY
ICRDGTTRRWICHCFMAVKDTGERLSHAVGCAFAACLER
Ligand information
>5njj Chain F (length=7) Species:
9606
(Homo sapiens) [
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AYIGPYL
Receptor-Ligand Complex Structure
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PDB
5njj
A Numb-Mdm2 fuzzy complex reveals an isoform-specific involvement of Numb in breast cancer.
Resolution
2.7 Å
Binding residue
(original residue number in PDB)
E112 K113 V114 S115 F116 C117 R132 S155 H156 G159 F162
Binding residue
(residue number reindexed from 1)
E83 K84 V85 S86 F87 C88 R103 S126 H127 G130 F133
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:5njj
,
PDBe:5njj
,
PDBj:5njj
PDBsum
5njj
PubMed
29269425
UniProt
P49757
|NUMB_HUMAN Protein numb homolog (Gene Name=NUMB)
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