Structure of PDB 5n9p Chain B Binding Site BS01
Receptor Information
>5n9p Chain B (length=111) Species:
9606
(Homo sapiens) [
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MSEQSICQARAAVMVYDDANKKWVPAGGSTGFSRVHIYHHTGNNTFRVVG
RKIQDHQVVINCAIPKGLKYNQATQTFHQWRDARQVYGLNFGSKEDANVF
ASAMMHALEVL
Ligand information
>5n9p Chain C (length=3) Species:
32630
(synthetic construct) [
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PPt
Receptor-Ligand Complex Structure
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PDB
5n9p
Designed nanomolar small-molecule inhibitors of Ena/VASP EVH1 interaction impair invasion and extravasation of breast cancer cells.
Resolution
1.8 Å
Binding residue
(original residue number in PDB)
Y16 W23 N71 F77 Q79 R81 V86
Binding residue
(residue number reindexed from 1)
Y16 W23 N71 F77 Q79 R81 V86
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:5n9p
,
PDBe:5n9p
,
PDBj:5n9p
PDBsum
5n9p
PubMed
33184177
UniProt
Q8N8S7
|ENAH_HUMAN Protein enabled homolog (Gene Name=ENAH)
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