Structure of PDB 5n9c Chain B Binding Site BS01

Receptor Information
>5n9c Chain B (length=110) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SEQSICQARAAVMVYDDANKKWVPAGGSTGFSRVHIYHHTGNNTFRVVGR
KIQDHQVVINCAIPKGLKYNQATQTFHQWRDARQVYGLNFGSKEDANVFA
SAMMHALEVL
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5n9c Designed nanomolar small-molecule inhibitors of Ena/VASP EVH1 interaction impair invasion and extravasation of breast cancer cells.
Resolution1.16 Å
Binding residue
(original residue number in PDB)
Y16 W23 K69 N71 F77 Q79 R81 V86
Binding residue
(residue number reindexed from 1)
Y15 W22 K68 N70 F76 Q78 R80 V85
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:5n9c, PDBe:5n9c, PDBj:5n9c
PDBsum5n9c
PubMed33184177
UniProtQ8N8S7|ENAH_HUMAN Protein enabled homolog (Gene Name=ENAH)

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