Structure of PDB 5n2j Chain B Binding Site BS01

Receptor Information
>5n2j Chain B (length=1381) Species: 759272 (Thermochaetoides thermophila DSM 1495) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ASPSINVALKAAFPSPPYLVELLETAASDNTTIYYSLLDRIAKGHFAEAT
TDKALYEKFLEVLRDDGHMDPEALSAFKLALSLRTATPRVEAHYQYYTAT
VEPSLSGTQEGCDQWFLIDGEQYCSPTLDTSHGKVKGEDQLRTLPFDRKF
GVGSRDVILYADITSKSFAPFHEVAMDLAKKGKASYRVRYRRSPSHSRES
LSVNGYGVELVLKRTDYIVIADIKPLEKSELAALGMKAASFVMQSEKPFE
ALLKLTQDFPKYSNSLGSQNVSAEFEAEHRGNREVFLPEGSNVLWLNGLH
LIDRQIQPFGLVDLLTRERKLIKSVLDLGLTGQQAVDLLGHAEVAHAKSG
DDEPRRFDWRDDIEEGQVIIWLNNLEKDKRYKSFSPSIWVLIHHFGHGLP
QIRRDVFNLVVPVDLTKADDVKIVVEGLLSFVKRLIPVRFGFVPLTPTGQ
AIDQAKVVYYLLENYGLAAATAYLEKSYEEQSTGQPNERIFNEVIKDKSL
RPDGVELSFKDIFISEKHEKQIHLSKHWVERLRAGGDVPTVFFDGFPIPR
EDNWLRVMNHRLMQDLQALQQAGYFGMLNESMWLPGFFLEKALSRRNTLI
FPEDKNELTVLNVNKIYIENHDLMSKVPVIEASKESTRDDWAALTVVADL
DDIEGQELVYYALRFRKSNDGVRLDIVHNPKDTSRSPSVLAQRLKSREDK
LLDFTRFLDLETALETGEFEPDVAYDASLANFLASSNMKAGDNFVILNGR
VLGPITSADDFKKEDFEVFLQAERRTRILPVYKALEDLGLDDKVSGPLSA
AKLTSVTALSTISDLPQGIFDNAPTVRTTLFKQWNSTYTSFEVGDASTAT
IFFVAVINPASEIGQRWVAVLKVLSELEGVHLRVFLNPTVMIEELPVKRF
YRYVLSSSPSFDESGKVKALSARFTGVPRETLLVVGMDVPPAWLVTSKVA
VDDLDNLRIKDIKAKRGTEHVEAIYELEHILIEGHSREIPGAHAPRGVQL
VLETENNPHFADTIIMANLGYFQFKANPGVYNIRLKEGRSSEIFTLESVG
AKGWGPIPGDDNTEVVLMDFQGTTLYPRLRRKPGMEEEDVLEPEATKSVS
KTEHAEINIFSVASGHLYERMLNIMMASVMHHTNHTVKFWFIEQFLSPSF
KDFIPHMAAEYGFKYEMVTYKWPHWLRQQKEKQREIWGYKILFLDVLFPL
SLDKVIFVDADQIVRTDMYDLVEHPLDGAPYGFAPMCDSRVEMEGYRFWK
TGYWANYLKGKPYHISALYVVDLQRFRELAAGDRLRQQYHALSADPNSLA
NLDQDLPNHMQFTIPIATLPQEWLWCETWCSDETLKDARTIDLCNNPMTK
EPKLDRARRQVPEWTKYDEEIAELARRVREE
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain5n2j Chain B Residue 1613 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5n2j Interdomain conformational flexibility underpins the activity of UGGT, the eukaryotic glycoprotein secretion checkpoint.
Resolution4.4 Å
Binding residue
(original residue number in PDB)		D1302 D1304 D1435
Binding residue
(residue number reindexed from 1)		D1209 D1211 D1342
Annotation score1
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003980 UDP-glucose:glycoprotein glucosyltransferase activity
Biological Process
GO:0006486 protein glycosylation

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Molecular Function
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Biological Process
External links
PDB RCSB:5n2j, PDBe:5n2j, PDBj:5n2j
PDBsum5n2j
PubMed28739903
UniProtG0SB58

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