Structure of PDB 5mg7 Chain B Binding Site BS01
Receptor Information
>5mg7 Chain B (length=199) Species:
9606
(Homo sapiens) [
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SSSVPSQKTYQGSYGFRLGFLHSGTAKSVTCTYSPALNKMFCQLAKTCPV
QLWVDSTPPPGTRVRAMAIYKQSQHMTEVVRRCPHHERCDSDGLAPPQHL
IRVEGNLRVEYLDDRNTFRHSVVVPYEPPEVGSDCTTIHYNYMCNSSCMG
GMNRRPILTIITLEDSSGNLLGRNSFEVRVCACPGRDRRTEEENLRKKG
Ligand information
>5mg7 Chain C (length=20) [
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tgacatgcccaggcatgtct
Receptor-Ligand Complex Structure
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PDB
5mg7
New Insights into the Role of DNA Shape on Its Recognition by p53 Proteins.
Resolution
1.45 Å
Binding residue
(original residue number in PDB)
A119 K120 R248
Binding residue
(residue number reindexed from 1)
A26 K27 R154
Enzymatic activity
Enzyme Commision number
?
Gene Ontology
Molecular Function
GO:0000976
transcription cis-regulatory region binding
GO:0003677
DNA binding
GO:0003700
DNA-binding transcription factor activity
Biological Process
GO:0006355
regulation of DNA-templated transcription
GO:0006915
apoptotic process
Cellular Component
GO:0005634
nucleus
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Molecular Function
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Cellular Component
External links
PDB
RCSB:5mg7
,
PDBe:5mg7
,
PDBj:5mg7
PDBsum
5mg7
PubMed
30057026
UniProt
P04637
|P53_HUMAN Cellular tumor antigen p53 (Gene Name=TP53)
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