Structure of PDB 5mb9 Chain B Binding Site BS01

Receptor Information
>5mb9 Chain B (length=491) Species: 759272 (Thermochaetoides thermophila DSM 1495) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ERVVIGITFGNSNSSIAHTVDDKAEVIANEDGDRQIPTILSYVDGDEYYG
QQAKNFLVRNPKNTVAYFRDILGQDFKSVDPTHNHASAHPQEAGDNVVFT
IKDKAEEDAEPSTLTVSEIATRYLRRLVGAASEYLGKKVTSAVITIPTNF
TEKQKAALIAAAAAADLEVLQLISEPAAAVLAYDARPEATISDKIIVVAD
LGGSRSDVTVLASRSGMYTILATVHDYEYHGIALDKVLIDHFSKEFLKKN
PGAKDPRENPRSLAKLRLEAESTKRALSRSTNASFSVESLIDGLDFASTI
NRLRYETIARTVFEGFNRLVESAVKKAGLDPLDVDEVIMSGGTSNTPRIA
ANFRYIFPESTRILAPSTDPSALNPSELQARGAALQASLIQEFETEDIEQ
STHAAVTTMPHVTNAIGVVSVSFVPIIAPETAVPARRTVHVLVKVVEGST
HINVREKVWKIGSTLAEAAVKVEVTINVNTDLTVIVTAREV
Ligand information
>5mb9 Chain C (length=29) Species: 759272 (Thermochaetoides thermophila DSM 1495) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
LTQEGSSMRTLEPVGPHFLAHARRVRHKR
Receptor-Ligand Complex Structure
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PDB5mb9 Structural insights into a unique Hsp70-Hsp40 interaction in the eukaryotic ribosome-associated complex.
Resolution3.2 Å
Binding residue
(original residue number in PDB)		Q182 I184 S185 I202 M228 Y229 Q397 L400 F404 D408 A416 V417 T418 M420 P421 H422 V423 T424 E447 L557
Binding residue
(residue number reindexed from 1)		Q171 I173 S174 I191 M217 Y218 Q386 L389 F393 D397 A405 V406 T407 M409 P410 H411 V412 T413 E430 L482
Enzymatic activity
Catalytic site (original residue number in PDB) T19 R80 E186 D211
Catalytic site (residue number reindexed from 1) T8 R69 E175 D200
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0140662 ATP-dependent protein folding chaperone
Biological Process
GO:0006457 protein folding
Cellular Component
GO:0005634 nucleus
GO:0005829 cytosol

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5mb9, PDBe:5mb9, PDBj:5mb9
PDBsum5mb9
PubMed28067917
UniProtG0RZX9

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