Structure of PDB 5lm5 Chain B Binding Site BS01

Receptor Information
>5lm5 Chain B (length=315) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
NLNKSGGKKFILELIETVYEEILDLEANLRNGQQTDSTAMWEALHIDDSS
YDVNPFISMLSFDKGIKIMPRIFNFLDKQQKLKILQKIFNELSHLQIIIL
SSYKTTPKPTLTQLKKVDLFQMIILKIIVSFLSNFIEIMGLLLQLIRNNN
VSFLTTSKIGLNLITILISRAALIKQDISTWNEIYDKLFTSLESKIQLIF
PPREYNDHIMRLQNDKFMDEAYIWAFLASLAASGKLNHQRIIIDEVRDEI
FATINEAETLQKKEKELSVLPQRSQELDTELKSIIYNKEKLYQDLNLFLN
VMGLVYRDGEISELK
Ligand information
>5lm5 Chain D (length=12) Species: 4932 (Saccharomyces cerevisiae) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
SSPGQLLDILNS
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5lm5 A unique surface on Pat1 C-terminal domain directly interacts with Dcp2 decapping enzyme and Xrn1 5'-3' mRNA exonuclease in yeast.
Resolution2.6 Å
Binding residue
(original residue number in PDB)		L717 Q720 R721 R728 F732 M783 G784 L785 I792 E794
Binding residue
(residue number reindexed from 1)		L236 Q239 R240 R247 F251 M302 G303 L304 I311 E313
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA

View graph for
Biological Process
External links
PDB RCSB:5lm5, PDBe:5lm5, PDBj:5lm5
PDBsum5lm5
PubMed29078363
UniProtP25644|PAT1_YEAST Deadenylation-dependent mRNA-decapping factor PAT1 (Gene Name=PAT1)

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