Structure of PDB 5lf2 Chain B Binding Site BS01

Receptor Information
>5lf2 Chain B (length=302) Species: 10116 (Rattus norvegicus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PCDCDVGGALDPQCDEATGQCRCRPHMIGRRCEQVQPGYFRPFLDHLTWE
AEGAHGQVLEVVERLVTNRETPSWTGVGFVRLREGQEVEFLVTSLPRAMD
YDLLLRWEPQVPEQWAELELVVQRPGPVSAHSPCGHVLPRDDRIQGMLHP
NTRVLVFPRPVCLEPGLSYKLKLKLTGTGGRGSGILIDSLVLQPHVLMLE
MFSGGDAAALERRTTFERYRCHEEGLMPSKTPLSEACVPLLISASSLVYN
GALPCQCDPQGSLSSECNPHGGQCRCKPGVVGRRCDACATGYYGFGPAGC
QA
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0
[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain5lf2 Chain B Residue 901 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5lf2 Crystallographic analysis of the laminin beta 2 short arm reveals how the LF domain is inserted into a regular array of LE domains.
Resolution1.85 Å
Binding residue
(original residue number in PDB)
E573 E575 T598 G601 D719
Binding residue
(residue number reindexed from 1)
E50 E52 T75 G78 D188
Annotation score4
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:5lf2, PDBe:5lf2, PDBj:5lf2
PDBsum5lf2
PubMed27425256
UniProtP15800|LAMB2_RAT Laminin subunit beta-2 (Gene Name=Lamb2)

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