Structure of PDB 5lde Chain B Binding Site BS01

Receptor Information
>5lde Chain B (length=225) Species: 1320,868565 [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
QYKLILGETTTEAVDAATAEKVFKQYANDNGVDGEWTYTKTFTVELEVLG
PLDPNSMATYEVLCEVARKLGTDDREVVLFLLNVFIPQPTLAQLIGALRA
LKEEGRLTFPLLAECLFRAGRRDLLRDLLHLDPRFLERHLAGTMSYFSPY
QLTVLHVDGELCARDIRSLIFLSKDTITPQTFLHWVYCMENLDLLGPTDV
DALMSMLRSLSRVDLQRQVQTLMGL
Ligand information
>5lde Chain R (length=20) Species: 9606 (Homo sapiens) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
LQVAYHALFQAYDNHIKSSC
Receptor-Ligand Complex Structure
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PDB5lde IKK gamma-Mimetic Peptides Block the Resistance to Apoptosis Associated with Kaposi's Sarcoma-Associated Herpesvirus Infection.
Resolution3.38 Å
Binding residue
(original residue number in PDB)		P154 A157 L173 H174 L175 D176 F179 H183 Y190
Binding residue
(residue number reindexed from 1)		P110 A113 L129 H130 L131 D132 F135 H139 Y146
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0006915 apoptotic process
GO:0042981 regulation of apoptotic process
GO:0052150 symbiont-mediated perturbation of host apoptosis
GO:0085033 symbiont-mediated activation of host NF-kappaB cascade
Cellular Component
GO:0005618 cell wall

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Biological Process
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Cellular Component
External links
PDB RCSB:5lde, PDBe:5lde, PDBj:5lde
PDBsum5lde
PubMed28931678
UniProtF5HEZ4;
P19909|SPG2_STRSG Immunoglobulin G-binding protein G (Gene Name=spg)

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