Structure of PDB 5kyu Chain B Binding Site BS01

Receptor Information
>5kyu Chain B (length=764) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SPIQVIENDRASRGGQVYATNTRGQIPPLVTTDCMIQDQGNASPRFIRCT
TYCFPCTSDMAKQAQIPLAAVIKPFATIPSNESPLYLVNHGESGPVRCNR
CKAYMCPFMQFIEGGRRYQCGFCNCVNDVPPFYFQHLDHIGRRLDHYEKP
ELSLGSYEYVATLDYCRKSKPPNPPAFIFMIDVSYSNIKNGLVKLICEEL
KTMLEKIPKEEQEETSAIRVGFITYNKVLHFFNVKSNLAQPQMMVVTDVG
EVFVPLLDGFLVNYQESQSVIHNLLDQIPDMFADSNENETVFAPVIQAGM
EALKAADCPGKLFIFHSSLPTAEAPGKLKNRDDKKLVNTDKEKILFQPQT
NVYDSLAKDCVAHGCSVTLFLFPSQYVDVASLGLVPQLTGGTLYKYNNFQ
MHLDRQQFLNDLRNDIEKKIGFDAIMRVRTSTGFRATDFFGGILMNNTTD
VEMAAIDCDKAVTVEFKHDDKLSEDSGALIQCAVLYTTISGQRRLRIHNL
GLNCSSQLADLYKSCETDALINFFAKSAFKAVLHQPLKVIREILVNQTAH
MLACYRKNCASPSAASQLILPDSMKVLPVYMNCLLKNCVLLSRPEISTDE
RAYQRQLVMTMGVADSQLFFYPQLLPIHTLDVKSTMLPAAVRCSESRLSE
EGIFLLANGLHMFLWLGVSSPPELIQGIFNVPSFAHINTDMTLLPEVGNP
YSQQLRMIMGIIQQKRPYSMKLTIVKQREQPEMVFRQFLVEDKGGSSYVD
FLCCVHKEICQLLN
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain5kyu Chain B Residue 1101 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5kyu TANGO1/cTAGE5 receptor as a polyvalent template for assembly of large COPII coats.
Resolution3.512 Å
Binding residue
(original residue number in PDB)		C364 C367 C386 C389
Binding residue
(residue number reindexed from 1)		C98 C101 C120 C123
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0008270 zinc ion binding
Biological Process
GO:0006886 intracellular protein transport
GO:0006888 endoplasmic reticulum to Golgi vesicle-mediated transport
Cellular Component
GO:0030127 COPII vesicle coat

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5kyu, PDBe:5kyu, PDBj:5kyu
PDBsum5kyu
PubMed27551091
UniProtO94855|SC24D_HUMAN Protein transport protein Sec24D (Gene Name=SEC24D)

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