Structure of PDB 5krm Chain B Binding Site BS01
Receptor Information
>5krm Chain B (length=240) Species:
9606
(Homo sapiens) [
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SLALSLTADQMVSALLDAEPPILYSEYDPRPFSEASMMGLLTNLADRELV
HMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFA
PNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLN
SGVYTFLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLL
ILSHIRHMSNKGMEHLYSMKCKNVVPLSDLLLEMLDAHRL
Ligand information
>5krm Chain D (length=10) Species:
9606
(Homo sapiens) [
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KILHRLLQDS
Receptor-Ligand Complex Structure
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PDB
5krm
Systems Structural Biology Analysis of Ligand Effects on ER alpha Predicts Cellular Response to Environmental Estrogens and Anti-hormone Therapies.
Resolution
2.24 Å
Binding residue
(original residue number in PDB)
I358 N359 K362 L372 V376 D538 L539 E542
Binding residue
(residue number reindexed from 1)
I53 N54 K57 L67 V71 D229 L230 E233
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:5krm
,
PDBe:5krm
,
PDBj:5krm
PDBsum
5krm
PubMed
28042045
UniProt
P03372
|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)
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