Structure of PDB 5krk Chain B Binding Site BS01

Receptor Information
>5krk Chain B (length=221) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
LALSLTADQMVSALLDAEPPILYSETRPFSEASMMGLLTNLADRELVHMI
NWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNL
LLDRNQEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTLE
EKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNK
GMEHLYSMKLSDLLLEMLDAH
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5krk Systems Structural Biology Analysis of Ligand Effects on ER alpha Predicts Cellular Response to Environmental Estrogens and Anti-hormone Therapies.
Resolution2.391 Å
Binding residue
(original residue number in PDB)
I358 K362 L372 V376 L539 E542
Binding residue
(residue number reindexed from 1)
I50 K54 L64 V68 L213 E216
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:5krk, PDBe:5krk, PDBj:5krk
PDBsum5krk
PubMed28042045
UniProtP03372|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)

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