Structure of PDB 5krh Chain B Binding Site BS01
Receptor Information
>5krh Chain B (length=237) Species:
9606
(Homo sapiens) [
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SLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADREL
VHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLF
APNLLLDRNQCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNS
GVYTFKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLIL
SHIRHMSNKGMEHLYSMKCKNVVPLSDLLLEMLDAHR
Ligand information
>5krh Chain D (length=10) Species:
9606
(Homo sapiens) [
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HKILHRLLQD
Receptor-Ligand Complex Structure
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PDB
5krh
Systems Structural Biology Analysis of Ligand Effects on ER alpha Predicts Cellular Response to Environmental Estrogens and Anti-hormone Therapies.
Resolution
2.243 Å
Binding residue
(original residue number in PDB)
I358 L372 Q375 V376 L379 D538 L539 E542
Binding residue
(residue number reindexed from 1)
I54 L68 Q71 V72 L75 D227 L228 E231
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:5krh
,
PDBe:5krh
,
PDBj:5krh
PDBsum
5krh
PubMed
28042045
UniProt
P03372
|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)
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