Structure of PDB 5krf Chain B Binding Site BS01
Receptor Information
>5krf Chain B (length=236) Species:
9606
(Homo sapiens) [
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SLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADREL
VHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLF
APNLLLDRNQGKMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGV
YTLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSH
IRHMSNKGMEHLYSMKCKNVVPLSDLLLEMLDAHRL
Ligand information
>5krf Chain D (length=10) Species:
32630
(synthetic construct) [
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HKILHRLLQD
Receptor-Ligand Complex Structure
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PDB
5krf
Systems Structural Biology Analysis of Ligand Effects on ER alpha Predicts Cellular Response to Environmental Estrogens and Anti-hormone Therapies.
Resolution
2.193 Å
Binding residue
(original residue number in PDB)
I358 K362 L372 Q375 V376 L379 E380 D538 E542
Binding residue
(residue number reindexed from 1)
I54 K58 L68 Q71 V72 L75 E76 D225 E229
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:5krf
,
PDBe:5krf
,
PDBj:5krf
PDBsum
5krf
PubMed
28042045
UniProt
P03372
|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)
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