Structure of PDB 5kd9 Chain B Binding Site BS01
Receptor Information
>5kd9 Chain B (length=228) Species:
9606
(Homo sapiens) [
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SLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADREL
VHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLF
APNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILL
NSGVYTEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSH
IRHMSNKGMEHLYSVPLSDLLLEMLDAH
Ligand information
>5kd9 Chain D (length=9) Species:
9606
(Homo sapiens) [
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KILHRLLQD
Receptor-Ligand Complex Structure
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PDB
5kd9
Full antagonism of the estrogen receptor without a prototypical ligand side chain.
Resolution
1.78 Å
Binding residue
(original residue number in PDB)
I358 K362 L372 V376 E542 M543
Binding residue
(residue number reindexed from 1)
I54 K58 L68 V72 E223 M224
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:5kd9
,
PDBe:5kd9
,
PDBj:5kd9
PDBsum
5kd9
PubMed
27870835
UniProt
P03372
|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)
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