Structure of PDB 5kcf Chain B Binding Site BS01
Receptor Information
>5kcf Chain B (length=227) Species:
9606
(Homo sapiens) [
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SLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADREL
VHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLF
APNLLLDRNQMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYT
FLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHI
RHMSNKGMEHLYSPLSDLLLEMLDAHR
Ligand information
>5kcf Chain C (length=9) Species:
9606
(Homo sapiens) [
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KILHRLLQD
Receptor-Ligand Complex Structure
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PDB
5kcf
Full antagonism of the estrogen receptor without a prototypical ligand side chain.
Resolution
2.07 Å
Binding residue
(original residue number in PDB)
I358 K362 L372 V376 L379 D538 L539 E542 M543
Binding residue
(residue number reindexed from 1)
I54 K58 L68 V72 L75 D217 L218 E221 M222
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:5kcf
,
PDBe:5kcf
,
PDBj:5kcf
PDBsum
5kcf
PubMed
27870835
UniProt
P03372
|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)
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