Structure of PDB 5kce Chain B Binding Site BS01
Receptor Information
>5kce Chain B (length=239) Species:
9606
(Homo sapiens) [
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SLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADREL
VHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLF
APNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILL
NSGVYTFLSSTLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRL
AQLLLILSHIRHMSNKGMEHLYSMKPLSDLLLEMLDAHR
Ligand information
>5kce Chain C (length=10) Species:
9606
(Homo sapiens) [
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HKILHRLLQD
Receptor-Ligand Complex Structure
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PDB
5kce
Full antagonism of the estrogen receptor without a prototypical ligand side chain.
Resolution
1.847 Å
Binding residue
(original residue number in PDB)
I358 V376 E380 L539 E542
Binding residue
(residue number reindexed from 1)
I54 V72 E76 L230 E233
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:5kce
,
PDBe:5kce
,
PDBj:5kce
PDBsum
5kce
PubMed
27870835
UniProt
P03372
|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)
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