Structure of PDB 5kcd Chain B Binding Site BS01
Receptor Information
>5kcd Chain B (length=226) Species:
9606
(Homo sapiens) [
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SLALSLTADQMVSALLDAEPPILYSEYFSEASMMGLLTNLADRELVHMIN
WAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLL
LDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSEEK
DHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGM
EHLYSMKCKNVVPLSDLLLEMLDAHR
Ligand information
>5kcd Chain D (length=9) Species:
9606
(Homo sapiens) [
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KILHRLLQD
Receptor-Ligand Complex Structure
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PDB
5kcd
Full antagonism of the estrogen receptor without a prototypical ligand side chain.
Resolution
1.82 Å
Binding residue
(original residue number in PDB)
I358 K362 L372 Q375 V376 E380 D538 L539 E542
Binding residue
(residue number reindexed from 1)
I49 K53 L63 Q66 V67 E71 D216 L217 E220
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:5kcd
,
PDBe:5kcd
,
PDBj:5kcd
PDBsum
5kcd
PubMed
27870835
UniProt
P03372
|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)
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