Structure of PDB 5kcc Chain B Binding Site BS01
Receptor Information
>5kcc Chain B (length=227) Species:
9606
(Homo sapiens) [
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NSLALSLTADQMVSALLDAEPPILYSEYFSEASMMGLLTNLADRELVHMI
NWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNL
LLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGV
YTDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNK
GMEHLYSMKNVVPLSDLLLEMLDAHRL
Ligand information
>5kcc Chain D (length=9) Species:
9606
(Homo sapiens) [
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HKILHRLLQ
Receptor-Ligand Complex Structure
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PDB
5kcc
Full antagonism of the estrogen receptor without a prototypical ligand side chain.
Resolution
2.386 Å
Binding residue
(original residue number in PDB)
I358 V376 E380 D538 L539 E542
Binding residue
(residue number reindexed from 1)
I50 V68 E72 D216 L217 E220
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:5kcc
,
PDBe:5kcc
,
PDBj:5kcc
PDBsum
5kcc
PubMed
27870835
UniProt
P03372
|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)
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