Structure of PDB 5jzj Chain B Binding Site BS01

Receptor Information

>5jzj Chain B (length=261) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

IPATITERYKVGRTIGDGNFAVVKECVERSTAREYALKIIKKSKCRGKEH
MIQNEVSILRRVKHPNIVLLIEEMDVPTELYLVMELVKGGDLFDAITSTN
KYTERDASGMLYNLASAIKYLHSLNIVHRDIKPENLLVYEHQDGSKSLKL
GDFGLATIVDGPLYTVCGTPTYVAPEIIAETGYGLKVDIWAAGVITYILL
CGFPPFREVLFDQILMGQVDFPSPYWDNVSDSAKELITMMLLVDVDQRFS
AVQVLEHPWVN

Ligand information

Ligand ID

InChI

InChI=1S/Mg/q+2

InChIKey

JLVVSXFLKOJNIY-UHFFFAOYSA-N

SMILES

Software	SMILES
ACDLabs 10.04 OpenEye OEToolkits 1.5.0	[Mg+2]
CACTVS 3.341	[Mg++]

Formula

Name

MAGNESIUM ION

PDB chain

5jzj Chain B Residue 901 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

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Structure summary

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PDB	5jzj Biochemical and Structural Insights into Doublecortin-like Kinase Domain 1.
Resolution	1.71 Å
Binding residue (original residue number in PDB)	N516 D533
Binding residue (residue number reindexed from 1)	N135 D152
Annotation score	1

Enzymatic activity

Catalytic site (original residue number in PDB)	D511 K513 E515 N516 D533 T550
Catalytic site (residue number reindexed from 1)	D130 K132 E134 N135 D152 T169
Enzyme Commision number	2.7.11.1: non-specific serine/threonine protein kinase.

Gene Ontology

	Molecular Function
GO:0004672	protein kinase activity
GO:0005524	ATP binding

	Biological Process
GO:0006468	protein phosphorylation

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Molecular Function

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Biological Process

External links

PDB	RCSB:5jzj, PDBe:5jzj, PDBj:5jzj
PDBsum	5jzj
PubMed	27545623
UniProt	O15075\|DCLK1_HUMAN Serine/threonine-protein kinase DCLK1 (Gene Name=DCLK1)

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