Structure of PDB 5jja Chain B Binding Site BS01

Receptor Information
>5jja Chain B (length=333) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
IRDVPPADQEKLFIQKLRQCCVLFDFVSDPLSDLKWKEVKRAALSEMVEY
ITHNRNVITEPIYPEVVHMFAVNMFRTLPPEPTLEAAWPHLQLVYEFFLR
FLESPDFQPNIAKKYIDQKFVLQLLELFDSEDPRERDFLKTTLHRIYGKF
LGLRAYIRKQINNIFYRFIYETEHHNGIAELLEILGSIINGFALPLKEEH
KIFLLKVLLPLHKVKSLSVYHPQLAYCVVQFLEKDSTLTEPVVMALLKYW
PKTHSPKEVMFLNELEEILDVIEPSEFVKIMEPLFRQLAKCVSSPHFQVA
ERALYYWNNEYIMSLISDNAAKILPIMFPSLYR
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5jja Crystal structure of a PP2A B56-BubR1 complex and its implications for PP2A substrate recruitment and localization.
Resolution2.35 Å
Binding residue
(original residue number in PDB)		H187 L194 R197 S230 N233 G234 F235 K240 H243
Binding residue
(residue number reindexed from 1)		H144 L151 R154 S187 N190 G191 F192 K197 H200
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0019888 protein phosphatase regulator activity
Biological Process
GO:0007165 signal transduction
Cellular Component
GO:0000159 protein phosphatase type 2A complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5jja, PDBe:5jja, PDBj:5jja
PDBsum5jja
PubMed27350047
UniProtQ13362|2A5G_HUMAN Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform (Gene Name=PPP2R5C)

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