Structure of PDB 5j19 Chain B Binding Site BS01
Receptor Information
>5j19 Chain B (length=230) Species:
9606
(Homo sapiens) [
Search protein sequence
] [
Download receptor structure
] [
Download structure with residue number starting from 1
] [
View receptor structure
]
EFGEVVDCHLSDMLQQLHSVNASKPSERGLVRQEEAEDPACIPIFWVSKW
VDYSDKYGLGYQLCDNSVGVLFNDSTRLILYNDGDSLQYIERDGTESYLT
VSSHPNSLMKKITLLKYFRNYMSEHLLKAGANITPREGDELARLPYLRTW
FRTRSAIILHLSNGSVQINFFQDHTKLILCPLMAAVTYIDEKRDFRTYRL
SLLEEYGCCKELASRLRYARTMVDKLLSSR
Ligand information
>5j19 Chain C (length=9) Species:
7227
(Drosophila melanogaster) [
Search peptide sequence
] [
Download ligand structure
] [
Download structure with residue number starting from 1
] [
View ligand structure
]
NAAFSSTPK
Receptor-Ligand Complex Structure
Global view
Local view
Structure summary
[
Spin on
] [
Spin off
] [
Reset
]
[
High quality
] [
Low quality
]
[
White background
] [
Black background
]
[
Spin on
] [
Spin off
] [
Reset
]
[
High quality
] [
Low quality
]
[
White background
] [
Black background
]
PDB
5j19
Phospho-Pon Binding-Mediated Fine-Tuning of Plk1 Activity
Resolution
2.0 Å
Binding residue
(original residue number in PDB)
W414 V415 D416 Y417 Y485 H489 L490 L491 R516 F535 H538 K540
Binding residue
(residue number reindexed from 1)
W50 V51 D52 Y53 Y121 H125 L126 L127 R152 F171 H174 K176
Enzymatic activity
Enzyme Commision number
2.7.11.21
: polo kinase.
External links
PDB
RCSB:5j19
,
PDBe:5j19
,
PDBj:5j19
PDBsum
5j19
PubMed
27238966
UniProt
P53350
|PLK1_HUMAN Serine/threonine-protein kinase PLK1 (Gene Name=PLK1)
[
Back to BioLiP
]
