Structure of PDB 5hzz Chain B Binding Site BS01

Receptor Information
>5hzz Chain B (length=139) Species: 243230 (Deinococcus radiodurans R1 = ATCC 13939 = DSM 20539) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
CPPTNAERLHEFHRAIGAATPERPTPPPPELLRLRQTLLDEASAEVRAEI
DHLLARQAAGEALSAGDLAPLAHELADLLYVTYGALDQLGIDADAVFAEV
HRANLSKASGPRRADGKQLKPEGWRPADVRGVIERLQHA
Ligand information
Ligand IDMN
InChIInChI=1S/Mn/q+2
InChIKeyWAEMQWOKJMHJLA-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mn+2]
CACTVS 3.341[Mn++]
FormulaMn
NameMANGANESE (II) ION
ChEMBL
DrugBankDB06757
ZINC
PDB chain5hzz Chain B Residue 201 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5hzz Deinococcus radiodurans DR2231 is a two-metal-ion mechanism hydrolase with exclusive activity on dUTP.
Resolution1.801 Å
Binding residue
(original residue number in PDB)		E79 D82
Binding residue
(residue number reindexed from 1)		E74 D77
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0046872 metal ion binding
GO:0047429 nucleoside triphosphate diphosphatase activity

View graph for
Molecular Function
External links
PDB RCSB:5hzz, PDBe:5hzz, PDBj:5hzz
PDBsum5hzz
PubMed27739259
UniProtQ9RS96

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