Structure of PDB 5hyr Chain B Binding Site BS01
Receptor Information
>5hyr Chain B (length=223) Species:
9606
(Homo sapiens) [
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ALSLTADQMVSALLDAEPPILYSEYSEASMMGLLTNLADRELVHMINWAK
RVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDR
NQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTDH
IHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEH
LYSMKCKNVVPLSDLLLEMLDAH
Ligand information
>5hyr Chain G (length=11) Species:
32630
(synthetic construct) [
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HKKLHRKLQDS
Receptor-Ligand Complex Structure
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PDB
5hyr
Stapled Peptides with gamma-Methylated Hydrocarbon Chains for the Estrogen Receptor/Coactivator Interaction.
Resolution
2.271 Å
Binding residue
(original residue number in PDB)
I358 V376 E380 L539 E542
Binding residue
(residue number reindexed from 1)
I46 V64 E68 L215 E218
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:5hyr
,
PDBe:5hyr
,
PDBj:5hyr
PDBsum
5hyr
PubMed
26928945
UniProt
P03372
|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)
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