Structure of PDB 5hk3 Chain B Binding Site BS01
Receptor Information
>5hk3 Chain B (length=103) Species:
83332
(Mycobacterium tuberculosis H37Rv) [
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VISRAEIYWADLRRPVLVIQSDPYNASRLATVIAAVITSNDALAAMPGNV
DLPATTTRLPRDSVVNVTAIVTLNKTDLTDRVGEVPASLMHEVDRGLRRV
LDL
Ligand information
>5hk3 Chain C (length=5) [
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cuccu
Receptor-Ligand Complex Structure
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PDB
5hk3
Crystal structure of M. tuberculosis MazF-mt3 T52D-F62D mutant in complex with DNA
Resolution
1.56 Å
Binding residue
(original residue number in PDB)
W10 R24 R25 P26 T49 S50 N51 P71 R72 S74 D91
Binding residue
(residue number reindexed from 1)
W9 R13 R14 P15 T38 S39 N40 P60 R61 S63 D80
Enzymatic activity
Enzyme Commision number
3.1.27.-
Gene Ontology
Molecular Function
GO:0003677
DNA binding
GO:0004519
endonuclease activity
GO:0004521
RNA endonuclease activity
GO:0004540
RNA nuclease activity
GO:0005515
protein binding
Biological Process
GO:0006402
mRNA catabolic process
GO:0016075
rRNA catabolic process
GO:0044003
symbiont-mediated perturbation of host process
GO:0045926
negative regulation of growth
GO:0045927
positive regulation of growth
Cellular Component
GO:0005576
extracellular region
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Molecular Function
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Biological Process
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Cellular Component
External links
PDB
RCSB:5hk3
,
PDBe:5hk3
,
PDBj:5hk3
PDBsum
5hk3
PubMed
UniProt
P9WII3
|MAZF6_MYCTU Endoribonuclease MazF6 (Gene Name=mazF6)
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