Structure of PDB 5h9d Chain B Binding Site BS01

Receptor Information
>5h9d Chain B (length=318) Species: 1280 (Staphylococcus aureus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
AKLNMNNEIKKVEQRLEKAIKSKDSVLEQASLHLLSSGGKRVRPAFVILS
SQFGKDEQTSEQTYQVAVALELIHMATLVHDDVIDKSDKRRGKLTISKKW
DQTTAILTGNFLLALGLEHLMAVKDNRVHQLISESIVDVCRGELFQFQDQ
FNSQQTIINYLRRINRKTALLIQISTEVGAITSQSDKETVRKLKMIGHYI
GMSFQIIDDVLDFTSTEKKLGKPVGSDLLNGHITLPILLEMRKNPDFKLK
IEQLRRDSERKEFEECIQIIRKSDSIDEAKAVSSKYLSKALNLISELPDG
HPKSLLLSLTKKMGSRNT
Ligand information
>5h9d Chain L (length=17) Species: 1280 (Staphylococcus aureus) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
KHYLHDIQKSYLKSRGN
Receptor-Ligand Complex Structure
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PDB5h9d Structure, Function, and Inhibition of Staphylococcus aureus Heptaprenyl Diphosphate Synthase
Resolution2.68 Å
Binding residue
(original residue number in PDB)		I159 R163 V283 K286 Y287 K290
Binding residue
(residue number reindexed from 1)		I158 R162 V282 K285 Y286 K289
Enzymatic activity
Enzyme Commision number 2.5.1.30: heptaprenyl diphosphate synthase.
Gene Ontology
Molecular Function
GO:0000010 heptaprenyl diphosphate synthase activity
GO:0004659 prenyltransferase activity
GO:0016740 transferase activity
Biological Process
GO:0008299 isoprenoid biosynthetic process

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Molecular Function
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Biological Process
External links
PDB RCSB:5h9d, PDBe:5h9d, PDBj:5h9d
PDBsum5h9d
PubMed27457559
UniProtQ2FYG6

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