Structure of PDB 5h92 Chain B Binding Site BS01

Receptor Information
>5h92 Chain B (length=572) Species: 4577 (Zea mays) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KRSKVEIIKEKSNFLRYPLNEELVSEAPNINESAVQLIKFHGSYQQTDRD
VRGQKNYSFMLRTKNPCGKVPNQLYLAMDTLADEFGIGTLRLTTRQTFQL
HGVLKKNLKTVLSTVIKNMGSTLGACGDLNRNVLAPAAPYVKKDILFAQQ
TAENIAALLTPQSGAYYDLWVDGEKIMSAEEPPEVTKARNDNSHGTNFPD
SPEPIYGTQYLPRKFKVAVTAAGDNSVDILTNDIGVVVVSDDAGEPIGFN
IYVGGGMGRTHRVETTFPRLADPLGYVPKEDILYAIKAIVVTQRENGRRD
DRKYSRMKYMIDRWGIDRFRAEVEKYYGKKFESFRPLPEWQFNSYLGWQE
QGDGKLFYGVHVDNGRVGGQAKKTLREIIEKYNLDVSITPNQNLILCGID
QAWREPITTALAQAGLLEPKDVDPLNLTAMACPALPLCPLAQTEAERGIL
PILKRIRAVFNKVGIKDSESVVVRITGCPNGCARPYMAELGFVGDGPKSY
QIWLGGTPNQSTLAESFMDKVKLDDIEKVLEPLFTYWNGTRQEGESFGSF
TNRTGFDKLKEVVNKWAESPSA
Ligand information
Ligand IDSF4
InChIInChI=1S/4Fe.4S
InChIKeyLJBDFODJNLIPKO-UHFFFAOYSA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 2.0.7[S]12[Fe]3[S]4[Fe]1[S]5[Fe]2[S]3[Fe]45
CACTVS 3.385S1[Fe]S[Fe]1.S2[Fe]S[Fe]2
FormulaFe4 S4
NameIRON/SULFUR CLUSTER
ChEMBL
DrugBank
ZINC
PDB chain5h92 Chain B Residue 701 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB5h92 Structural and mutational studies of an electron transfer complex of maize sulfite reductase and ferredoxin.
Resolution2.08 Å
Binding residue
(original residue number in PDB)		C494 A496 C500 A503 T538 G539 C540 N542 C544
Binding residue
(residue number reindexed from 1)		C432 A434 C438 A441 T476 G477 C478 N480 C482
Annotation score1
Enzymatic activity
Catalytic site (original residue number in PDB) R124 R193 K276 K278 P452 C494 C500 C540 C544 A634
Catalytic site (residue number reindexed from 1) R62 R131 K214 K216 P390 C432 C438 C478 C482 A572
Enzyme Commision number 1.8.7.1: assimilatory sulfite reductase (ferredoxin).
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003690 double-stranded DNA binding
GO:0016002 sulfite reductase activity
GO:0016491 oxidoreductase activity
GO:0020037 heme binding
GO:0046872 metal ion binding
GO:0050311 sulfite reductase (ferredoxin) activity
GO:0051536 iron-sulfur cluster binding
GO:0051539 4 iron, 4 sulfur cluster binding
Biological Process
GO:0000103 sulfate assimilation
GO:0006790 sulfur compound metabolic process
GO:0009409 response to cold
GO:0019418 sulfide oxidation
GO:0045892 negative regulation of DNA-templated transcription
GO:1900160 plastid chromosome packaging
Cellular Component
GO:0009337 sulfite reductase complex (NADPH)
GO:0009507 chloroplast
GO:0009570 chloroplast stroma
GO:0010319 stromule
GO:0042644 chloroplast nucleoid

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5h92, PDBe:5h92, PDBj:5h92
PDBsum5h92
PubMed26920048
UniProtO23813|SIR_MAIZE Sulfite reductase [ferredoxin], chloroplastic (Gene Name=SIR)

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