Structure of PDB 5h7l Chain B Binding Site BS01

Receptor Information
>5h7l Chain B (length=691) Species: 70601 (Pyrococcus horikoshii OT3) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
IAKIKELMLQPERIRNIGIAAHIDHGKTTLSDNLLAGAGMAANVSMVHNY
EGKDYLINLIDTPGHVDFGGDVTRAMRAIDGVIIVVDAVEGVMPQTETVV
RQALREYVKPVLFINKVDRLIRELKLTPQQMMERFSKIIMDVNRLIQRYA
PEEYKKKWMVKVEDGSVAFGSAYYNWALSVPFMKRTGVKFNEIIDLTLKG
DNRTLRQKAPLHVVVLDMVVRHLPSPIEAQKYRIPHLWEGDISSDIGQAM
LNCDPKGKMVMVVTKIIIVATGRVWSGTVKSGQEVYLINTKRKARIQQVG
IYMGPERINMEAVPAGNIVAVTGLRDAMAGETVAEEQIEPFEALHYVSEP
VVTVAIEAKNVKDLPRLIEALRQLAKEDPTLHVKIDEETGQHLLSGMGEL
HLEVKLYKLKKDWGIDIEVSEPIVVYRESITKSSPMVEGKSPNRHNRFYI
VVEPMPDEIYNAIKEGIIPEGRVKNPKEVAKKLAELGMDYEIARGIVDIY
NGNMFIDNTKGVQYLNEVMDLLIDGFHQAMDEGPLAREPVMKVIVRLLDA
QVHEDNVHRGPAQIYPAIRTAIHCAMMKSNPVLYEPYQKVIINIPYEYMG
AVSREITQRRGQLVDMKQEGEVMTIIAEAPVAEMFGFAGSIRSATSGRAL
WSTEHAGFKRVPNELAQQIIRQIRQRKGLDPNPPTEKDVCP
Ligand information
>5h7l Chain G (length=10) Species: 70601 (Pyrococcus horikoshii OT3) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
ALAGLSALFG
Receptor-Ligand Complex Structure
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PDB5h7l The C-terminal helix of ribosomal P stalk recognizes a hydrophobic groove of elongation factor 2 in a novel fashion
Resolution3.1 Å
Binding residue
(original residue number in PDB)		P164 M168 S172 V198 E199 V216 M219 K225 F226
Binding residue
(residue number reindexed from 1)		P128 M132 S136 V162 E163 V180 M183 K189 F190
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003746 translation elongation factor activity
GO:0003924 GTPase activity
GO:0005525 GTP binding
Biological Process
GO:0006412 translation
GO:0006414 translational elongation
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:1990904 ribonucleoprotein complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5h7l, PDBe:5h7l, PDBj:5h7l
PDBsum5h7l
PubMed29471537
UniProtO59521|EF2_PYRHO Elongation factor 2 (Gene Name=fusA)

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