Structure of PDB 5gu4 Chain B Binding Site BS01

Receptor Information
>5gu4 Chain B (length=255) Species: 3988 (Ricinus communis) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
YPIINFTTAGATVQSYTNFIRAVRGRLTTGADVRHEIPVLPNRVGLPINQ
RFILVELSNHAELSVTLALDVTNAYVVGYRAGNSAYFFHPDNQEDAEAIT
HLFTDVQNRYTFAFGGNYDRLEQLAGNLRENIELGNGPLEEAISALYYYS
TGGTQLPTLARSFIICIQMISEAARFQYIEGEMRTRIRYNRRSAPDPSVI
TLENSWGRLSTAIQESNQGAFASPIQLQRRNGSKFSVYDVSILIPIIALM
VYRCA
Ligand information
Receptor-Ligand Complex Structure
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PDB5gu4 Crystal Structure of Ribosome-Inactivating Protein Ricin A Chain in Complex with the C-Terminal Peptide of the Ribosomal Stalk Protein P2
Resolution1.55 Å
Binding residue
(original residue number in PDB)		Q182 Y183 S203 R234 R235 F240 I247 P250 I251
Binding residue
(residue number reindexed from 1)		Q177 Y178 S198 R229 R230 F235 I242 P245 I246
Enzymatic activity
Catalytic site (original residue number in PDB) T13 V81 E177 R180
Catalytic site (residue number reindexed from 1) T8 V76 E172 R175
Enzyme Commision number 3.2.2.22: rRNA N-glycosylase.
Gene Ontology
Molecular Function
GO:0030598 rRNA N-glycosylase activity
Biological Process
GO:0017148 negative regulation of translation

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Molecular Function
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Biological Process
External links
PDB RCSB:5gu4, PDBe:5gu4, PDBj:5gu4
PDBsum5gu4
PubMed27754366
UniProtP02879|RICI_RICCO Ricin

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