Structure of PDB 5gr9 Chain B Binding Site BS01

Receptor Information

>5gr9 Chain B (length=595) Species: 3702 (Arabidopsis thaliana) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

KFSPQLLSLLSLKTSLSGPPSAFQDWKVPVDAVWCSWSGVVCDNVTAQVI
SLDLSHRNLSGRIPIQIRYLSSLLYLNLSGNSLEGSFPTSIFDLTKLTTL
DISRNSFDSSFPPGISKLKFLKVFNAFSNNFEGLLPSDVSRLRFLEELNF
GGSYFEGEIPAAYGGLQRLKFIHLAGNVLGGKLPPRLGLLTELQHMEIGY
NHFNGNIPSEFALLSNLKYFDVSNCSLSGSLPQELGNLSNLETLFLFQNG
FTGEIPESYSNLKSLKLLDFSSNQLSGSIPSGFSTLKNLTWLSLISNNLS
GEVPEGIGELPELTTLFLWNNNFTGVLPHKLGSNGKLETMDVSNNSFTGT
IPSSLCHGNKLYKLILFSNMFEGELPKSLTRCESLWRFRSQNNRLNGTIP
IGFGSLRNLTFVDLSNNRFTDQIPADFATAPVLQYLNLSTNFFHRKLPEN
IWKAPNLQIFSASFSNLIGEIPNYVGCKSFYRIELQGNSLNGTIPWDIGH
CEKLLCLNLSQNHLNGIIPWEISTLPSIADVDLSHNLLTGTIPSDFGSSK
TITTFNVSYNQLIGPIPSGSFAHLNPSFFSSNEGLCGDLVGKPCN

Ligand information

>5gr9 Chain C (length=12) Species: 3701 (Arabidopsis) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

HEVPSGPNPISN

Receptor-Ligand Complex Structure

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Structure summary

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PDB	5gr9 Crystal structure of PXY-TDIF complex reveals a conserved recognition mechanism among CLE peptide-receptor pairs
Resolution	2.767 Å
Binding residue (original residue number in PDB)	R138 F161 S162 G186 S187 G210 Y234 F279 F281 D303 W325 I329 W353 D375 K397 R421 R423
Binding residue (residue number reindexed from 1)	R104 F127 S128 G152 S153 G176 Y200 F245 F247 D269 W291 I295 W319 D341 K363 R387 R389

Enzymatic activity

Enzyme Commision number

2.7.11.1: non-specific serine/threonine protein kinase.

External links

PDB	RCSB:5gr9, PDBe:5gr9, PDBj:5gr9
PDBsum	5gr9
PubMed	27055373
UniProt	Q9FII5\|TDR_ARATH Leucine-rich repeat receptor-like protein kinase TDR (Gene Name=TDR)

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