Structure of PDB 5gpe Chain B Binding Site BS01

Receptor Information
>5gpe Chain B (length=124) Species: 266264 (Cupriavidus metallidurans CH34) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MMRIGELGKKADCLVQTVRFYESEGLLPEPARFRLYDEVHLQRLLFIRRC
RAKDMTLDEIRQLLNLRDRPELGCGEVNALVDAHIAQVRTKMKELRALER
ELMDLRRSCDARTSRECGILNSLA
Ligand information
Ligand IDPB
InChIInChI=1S/Pb/q+2
InChIKeyRVPVRDXYQKGNMQ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.370[Pb++]
valence
OpenEye OEToolkits 1.7.2[Pb+2]
FormulaPb
NameLEAD (II) ION
ChEMBL
DrugBank
ZINC
PDB chain5gpe Chain A Residue 201 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB5gpe Structural Basis for the Selective Pb(II) Recognition of Metalloregulatory Protein PbrR691
Resolution2.01 Å
Binding residue
(original residue number in PDB)		C113 C122
Binding residue
(residue number reindexed from 1)		C109 C117
Annotation score1
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
GO:0046872 metal ion binding
Biological Process
GO:0006355 regulation of DNA-templated transcription
GO:0045893 positive regulation of DNA-templated transcription

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:5gpe, PDBe:5gpe, PDBj:5gpe
PDBsum5gpe
PubMed27989185
UniProtQ1LKZ5

[Back to BioLiP]