Structure of PDB 5fww Chain B Binding Site BS01

Receptor Information
>5fww Chain B (length=288) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PECFTANGADYRGTQNWTALQGGKPCLFWNETFQHPYNTLKYPNGEGGLG
EHNYCRNPDGDVSPWCYVGVYWKYCEIPACQMPGNLGCYKDHGNPPPLTG
TSKTSNKLTIQTCISFCRSQRFKFAGMESGYACFCGNNPDYWKYGEAAST
ECNSVCFGDHTQPCGGDGRIILFDTLVGACGGNYSAMSSVVYSPDFPDTY
ATGRVCYWTIRVPGASHIHFSFPLFDIRDSADMVELLDGYTHRVLARFHG
RSRPPLSFNVSLDFVILYFFSDRINQAQGFAVLYQAVK
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain5fww Chain B Residue 1323 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB5fww Structure of the Dual-Mode Wnt Regulator Kremen1 and Insight Into Ternary Complex Formation with Lrp6 and Dickkopf
Resolution3.5 Å
Binding residue
(original residue number in PDB)		D266 S305 D306 N309
Binding residue
(residue number reindexed from 1)		D232 S271 D272 N275
Annotation score4
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:5fww, PDBe:5fww, PDBj:5fww
PDBsum5fww
PubMed27524201
UniProtQ96MU8|KREM1_HUMAN Kremen protein 1 (Gene Name=KREMEN1)

[Back to BioLiP]