Structure of PDB 5fny Chain B Binding Site BS01

Receptor Information

>5fny Chain B (length=218) Species: 83333 (Escherichia coli K-12)

YRDQPLGELALSIPRASALFRKYDMDYAAGGKQTLARAAARKELDVEVIE
AELAKLAEQPIEKDWRSAPLAEIIDHIIVRYHDRHREQLPELILQATKVE
RVHADKPSVPKGLTKYLTMLHEELSSHMMKEEQILFPMIKQGMGSQAMGP
ISVMESEHDEAGELLEVIKHTTNNVTPPPEACTTWKAMYNGINELIDDLM
DHISLENNVLFPRALAGE

Ligand information

• Ligand ID: FE
• InChI: InChI=1S/Fe/q+3
• InChIKey: VTLYFUHAOXGGBS-UHFFFAOYSA-N
• SMILES:
  ACDLabs 10.04
  CACTVS 3.341
  OpenEye OEToolkits 1.5.0: [Fe+3]
• Formula: Fe
• Name: FE (III) ION
• DrugBank: DB13949
• PDB chain: 5fny Chain B Residue 1221

Receptor-Ligand Complex Structure

Structure summary

• PDB: 5fny Crystal Structure of the Repair of Iron Centers Protein Ytfe and its Interaction with No
• Resolution: 2.01 Å
• Binding residue (original residue number in PDB): H84 E133 H204 E208
• Binding residue (residue number reindexed from 1): H82 E131 H202 E206
• Annotation score: 5

Enzymatic activity

• Enzyme Commision number: 1.7.2.5: nitric-oxide reductase (cytochrome c).

Gene Ontology

Molecular Function

• GO:0005506 iron ion binding
• GO:0005515 protein binding
• GO:0046872 metal ion binding
• GO:0098809 nitrite reductase activity

Biological Process

• GO:0006979 response to oxidative stress
• GO:0030091 protein repair
• GO:0051409 response to nitrosative stress

Cellular Component

• GO:0005737 cytoplasm
• GO:0005829 cytosol

External links

• PDB: RCSB:5fny, PDBe:5fny, PDBj:5fny
• PDBsum: 5fny
• PubMed: 27246459
• UniProt: P69506|YTFE_ECOLI Iron-sulfur cluster repair protein YtfE (Gene Name=ytfE)