Structure of PDB 5fmp Chain B Binding Site BS01

Receptor Information
>5fmp Chain B (length=183) Species: 83332 (Mycobacterium tuberculosis H37Rv) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SEAQRERRKRILDATMAIASKGGYEAVQMRAVADRADVAVGTLYRYFPSK
VHLLVSALGREFSRIDAKTDRSAVAGATPFQRLNFMVGKLNRAMQRNPLL
TEAMTRAYVFADASAASEVDQVEKLIDSMFARAMANGEPTEDQYHIARVI
SDVWLSNLLAWLTRRASATDVSKRLDLAVRLLI
Ligand information
Receptor-Ligand Complex Structure
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PDB5fmp Kstr, Transcriptional Repressor of Cholesterol Degradation in Mycobacterium Tuberculosis
Resolution2.26 Å
Binding residue
(original residue number in PDB)
Q59 R61 Y75 S80 K81
Binding residue
(residue number reindexed from 1)
Q28 R30 Y44 S49 K50
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0000976 transcription cis-regulatory region binding
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
GO:0042803 protein homodimerization activity
Biological Process
GO:0006355 regulation of DNA-templated transcription

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Molecular Function

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Biological Process
External links
PDB RCSB:5fmp, PDBe:5fmp, PDBj:5fmp
PDBsum5fmp
PubMed
UniProtP96856|KSTR_MYCTU HTH-type transcriptional repressor KstR (Gene Name=kstR)

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