Structure of PDB 5fgw Chain B Binding Site BS01

Receptor Information
>5fgw Chain B (length=247) Species: 1314 (Streptococcus pyogenes) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
WSIEQHPNYYHVEGKAQLDIKNFPELYRTTERVYKKSSTKPVTVSNIHYS
VLDGYGRSGEAYGIITKDMIDMSAGYREKWESKPEPSGWYSYFFKNTNQR
ATESDYKHSPKNVSKISNNIKASILLSNGNVRNGYLFDRSGLIADSLGGR
PFRNNLITGTRTQNVGNNDRKGGMQYIENKVLDHIKRNPKVHVYYKATPV
YQGSELLPRAVLVSALSSDGFIDETVRVFNNVAGFNIDYQNGGLLSS
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain5fgw Chain B Residue 301 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5fgw Structural characterization of the virulence factor Sda1 nuclease from Streptococcus pyogenes.
Resolution1.95 Å
Binding residue
(original residue number in PDB)		H51 H56
Binding residue
(residue number reindexed from 1)		H6 H11
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0016787 hydrolase activity
GO:0046872 metal ion binding

View graph for
Molecular Function
External links
PDB RCSB:5fgw, PDBe:5fgw, PDBj:5fgw
PDBsum5fgw
PubMed26969731
UniProtQ675N6

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