Structure of PDB 5fb9 Chain B Binding Site BS01
Receptor Information
>5fb9 Chain B (length=265) Species:
510516
(Aspergillus oryzae RIB40) [
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WGNLGHETVAYIAQSFVASSTESFCQNILGDDSTSYLANVATWADTYKYT
DAGEFSKPYHFIDAQDNPPQSCGVDYDRDCGSAGCSISAIQNYTNILLES
PNGSEALNALKFVVHIIGDIHQPLHDENLEAGGNGIDVTYDGETTNLHHI
WDTNMPEEAAGGYSLSVAKTYADLLTERIKTGTYSSKKDSWTDGIDIKDP
VSTSMIWAADANTYVCSTVLDDGLAYINSTDLSGEYYDKSQPVFEELIAK
AGYRLAAWLDLIASQ
Ligand information
Ligand ID
ZN
InChI
InChI=1S/Zn/q+2
InChIKey
PTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
Software
SMILES
CACTVS 3.341
[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0
[Zn+2]
Formula
Zn
Name
ZINC ION
ChEMBL
CHEMBL1236970
DrugBank
DB14532
ZINC
PDB chain
5fb9 Chain B Residue 401 [
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Receptor-Ligand Complex Structure
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PDB
5fb9
Structural and Catalytic Properties of S1 Nuclease from Aspergillus oryzae Responsible for Substrate Recognition, Cleavage, Non-Specificity, and Inhibition.
Resolution
1.5 Å
Binding residue
(original residue number in PDB)
W21 H26 D139
Binding residue
(residue number reindexed from 1)
W1 H6 D119
Annotation score
4
Enzymatic activity
Catalytic site (original residue number in PDB)
W21 H26 D65 K68 H80 H135 D139 H145 H168 D172
Catalytic site (residue number reindexed from 1)
W1 H6 D45 K48 H60 H115 D119 H125 H148 D152
Enzyme Commision number
3.1.30.1
: Aspergillus nuclease S1.
Gene Ontology
Molecular Function
GO:0003676
nucleic acid binding
GO:0004518
nuclease activity
GO:0004519
endonuclease activity
GO:0016788
hydrolase activity, acting on ester bonds
GO:0046872
metal ion binding
Biological Process
GO:0006308
DNA catabolic process
Cellular Component
GO:0005575
cellular_component
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Molecular Function
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Biological Process
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Cellular Component
External links
PDB
RCSB:5fb9
,
PDBe:5fb9
,
PDBj:5fb9
PDBsum
5fb9
PubMed
28036383
UniProt
P24021
|NUS1_ASPOR Nuclease S1 (Gene Name=nucS)
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