Structure of PDB 5f6c Chain B Binding Site BS01

Receptor Information
>5f6c Chain B (length=510) Species: 83333 (Escherichia coli K-12) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
HMKRMLINATQQEELRVALVDGQRLYDLDIESPGHEQKKANIYKGKITRI
EPSLEAAFVDYGAERHGFLPLKEIAREYFPANYSAHGRPNIKDVLREGQE
VIVQIDKEERGNKGAALTTFISLAGSYLVLMPNNPRAGGISRRIEGDDRT
ELKEALASLELPEGMGLIVRTAGVGKSAEALQWDLSFRLKHWEAIKKAAE
SRPAPFLIHQESNVIVRAFRDYLRQDIGEILIDNPKVLELARQHIAALGR
PDFSSKIKLYTGEIPLFSHYQIESQIESAFQREVRLPSGGSIVIDSTEAL
TAIRINSARATRGGDIEETAFNTNLEAADEIARQLRLRDLGGLIVIRFID
MTPVRHQRAVENRLREAVRQDRARIQISHISRFGLLEMSRQRLSPSLGES
SHHVCPRCSGTGTVRDNESLSLSILRLIEEEALKENTQEVHAIVPVPIAS
YLLNEKRSAVNAIETRQDGVRCVIVPNDQMETPHYHVLRVRKGEETPTLS
YMLPKLHEEA
Ligand information
Receptor-Ligand Complex Structure
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PDB5f6c Substrate Recognition and Autoinhibition in the Central Ribonuclease RNase E.
Resolution3.002 Å
Binding residue
(original residue number in PDB)		S121 V128 G137 I139 S140 R142 I167 R169 T170
Binding residue
(residue number reindexed from 1)		S122 V129 G138 I140 S141 R143 I168 R170 T171
Enzymatic activity
Enzyme Commision number 3.1.26.12: ribonuclease E.
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0003723 RNA binding
GO:0004540 RNA nuclease activity
GO:0008995 ribonuclease E activity
Biological Process
GO:0006396 RNA processing

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Molecular Function
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Biological Process
External links
PDB RCSB:5f6c, PDBe:5f6c, PDBj:5f6c
PDBsum5f6c
PubMed30270108
UniProtP21513|RNE_ECOLI Ribonuclease E (Gene Name=rne)

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