Structure of PDB 5ez0 Chain B Binding Site BS01
Receptor Information
>5ez0 Chain B (length=92) Species:
9606
(Homo sapiens) [
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IPHDNLVLIRMKPDENGRFGFNVKGGYDQKMPVIVSRVAPGTPADLCVPR
LNEGDQVVLINGRDIAEHTHDQVVLFIKASCSGELMLLVRPN
Ligand information
>5ez0 Chain F (length=6) Species:
9606
(Homo sapiens) [
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SKETPL
Receptor-Ligand Complex Structure
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PDB
5ez0
Molecular Basis of the Interaction of the Human Protein Tyrosine Phosphatase Non-receptor Type 4 (PTPN4) with the Mitogen-activated Protein Kinase p38 gamma.
Resolution
2.35 Å
Binding residue
(original residue number in PDB)
R527 F528 G529 F530 N531 V532 K533 Q538 S545 H579 V583 I586
Binding residue
(residue number reindexed from 1)
R18 F19 G20 F21 N22 V23 K24 Q29 S36 H70 V74 I77
Enzymatic activity
Enzyme Commision number
3.1.3.48
: protein-tyrosine-phosphatase.
External links
PDB
RCSB:5ez0
,
PDBe:5ez0
,
PDBj:5ez0
PDBsum
5ez0
PubMed
27246854
UniProt
P29074
|PTN4_HUMAN Tyrosine-protein phosphatase non-receptor type 4 (Gene Name=PTPN4)
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