Structure of PDB 5eyh Chain B Binding Site BS01

Receptor Information

>5eyh Chain B (length=258) Species: 1280 (Staphylococcus aureus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

KTLQQIDKLICSWLKQIDNVIPQLIMEMTTETKRLVTNVDKQIQQQFQQF
LATYFPEHQLLAEEKSNAMITNEINHLWIMDPIDGTANLVKQQEDYCIIL
AYFYEGKPMLSYVYDYPHKKLYKAIRGEGAFCNGFKMEEPPSLKLEDAII
SFNAQVMNLDTVQDLFDASFSYRLVGACGLDSMRVAKGQFGAHINTNPKP
WDIAAQFLFAELLNLKMTTLDGKAIDHLKGAPFIISNKACHETVLKILNA
NGGYQKYR

Ligand information

Ligand ID

InChI

InChI=1S/Ca/q+2

InChIKey

BHPQYMZQTOCNFJ-UHFFFAOYSA-N

SMILES

Software	SMILES
CACTVS 3.341	[Ca++]
ACDLabs 10.04 OpenEye OEToolkits 1.5.0	[Ca+2]

Formula

Name

CALCIUM ION

PDB chain

5eyh Chain B Residue 301 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

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Structure summary

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PDB	5eyh Structural elucidation of the NADP(H) phosphatase activity of staphylococcal dual-specific IMPase/NADP(H) phosphatase
Resolution	2.5 Å
Binding residue (original residue number in PDB)	D88 D91 D209
Binding residue (residue number reindexed from 1)	D81 D84 D202
Annotation score	1

Enzymatic activity

Catalytic site (original residue number in PDB)	E70 D88 I90 D91 T93 D209
Catalytic site (residue number reindexed from 1)	E63 D81 I83 D84 T86 D202
Enzyme Commision number	3.1.3.25: inositol-phosphate phosphatase.

Gene Ontology

	Molecular Function
GO:0000166	nucleotide binding
GO:0008934	inositol monophosphate 1-phosphatase activity
GO:0046872	metal ion binding

	Biological Process
GO:0006020	inositol metabolic process
GO:0007165	signal transduction

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Molecular Function

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Biological Process

External links

PDB	RCSB:5eyh, PDBe:5eyh, PDBj:5eyh
PDBsum	5eyh
PubMed	26894675
UniProt	Q2FVV7

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