Structure of PDB 5ero Chain B Binding Site BS01

Receptor Information
>5ero Chain B (length=300) Species: 1214568 (Diaporthe amygdali) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
HIFFEKAVLEAPYDYIASMPSKGVRDQFIDALNDWLRVPDVKVGKIKDAV
RVLHNSSLLLDDFQDNSPLRRGKPSTHNIFGSAQTVNTATYSIIKAIGQI
MEFSAGEEVMNSIMILFQGQAMDLFWTYNGHVPSEEEYYRMIDQKTGQLF
SIATSLLLNAADNEIPRTKIQSCLHRLTRLLGRCFQIRDDYQNLVSADYT
KQKGFCEDLDEGKWSLALIHMIHKQRSHMALLNVLSTGRKHGGMTLEQKQ
FVLDIIEEEKSLDYTRSVMMDLHVQLRAEIGRIEILLDSPNPAMRLLLEL
Ligand information
Ligand IDCO
InChIInChI=1S/Co/q+2
InChIKeyXLJKHNWPARRRJB-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Co+2]
CACTVS 3.341[Co++]
FormulaCo
NameCOBALT (II) ION
ChEMBL
DrugBankDB14205
ZINC
PDB chain5ero Chain B Residue 802 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB5ero Structure and Function of Fusicoccadiene Synthase, a Hexameric Bifunctional Diterpene Synthase.
Resolution2.55 Å
Binding residue
(original residue number in PDB)		D474 D478
Binding residue
(residue number reindexed from 1)		D61 D65
Annotation score1
Enzymatic activity
Enzyme Commision number 2.5.1.29: geranylgeranyl diphosphate synthase.
4.2.3.43: fusicocca-2,10(14)-diene synthase.
Gene Ontology
Molecular Function
GO:0004659 prenyltransferase activity
Biological Process
GO:0008299 isoprenoid biosynthetic process

View graph for
Molecular Function
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Biological Process
External links
PDB RCSB:5ero, PDBe:5ero, PDBj:5ero
PDBsum5ero
PubMed26734760
UniProtA2PZA5|FC1_PHOAM Fusicoccadiene synthase (Gene Name=PaFS)

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