Structure of PDB 5emp Chain B Binding Site BS01
Receptor Information
>5emp Chain B (length=71) Species:
9606
(Homo sapiens) [
Search protein sequence
] [
Download receptor structure
] [
Download structure with residue number starting from 1
] [
View receptor structure
]
KLCLVCSDEASGCHYGVLTCGSCKVFFKRAVEGQHNYLCAGRNDCIIDKI
RRKNCPACRYRKCLQAGMNLE
Ligand information
>5emp Chain C (length=18) [
Search DNA sequence
] [
Download ligand structure
] [
Download structure with residue number starting from 1
] [
View ligand structure
]
ccagaacatgatgttctg
Receptor-Ligand Complex Structure
Global view
Local view
Structure summary
[
Spin on
] [
Spin off
] [
Reset
]
[
High quality
] [
Low quality
]
[
White background
] [
Black background
]
[
Spin on
] [
Spin off
] [
Reset
]
[
High quality
] [
Low quality
]
[
White background
] [
Black background
]
PDB
5emp
The effects of cytosine methylation on general transcription factors
Resolution
2.3 Å
Binding residue
(original residue number in PDB)
S459 R466 R489 K490 R496 L507 E508
Binding residue
(residue number reindexed from 1)
S22 R29 R52 K53 R59 L70 E71
Enzymatic activity
Enzyme Commision number
?
Gene Ontology
Molecular Function
GO:0003700
DNA-binding transcription factor activity
GO:0008270
zinc ion binding
GO:0043565
sequence-specific DNA binding
Biological Process
GO:0006355
regulation of DNA-templated transcription
View graph for
Molecular Function
View graph for
Biological Process
External links
PDB
RCSB:5emp
,
PDBe:5emp
,
PDBj:5emp
PDBsum
5emp
PubMed
UniProt
P04150
|GCR_HUMAN Glucocorticoid receptor (Gene Name=NR3C1)
[
Back to BioLiP
]