Structure of PDB 5egv Chain B Binding Site BS01

Receptor Information
>5egv Chain B (length=232) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
LSLTADQMVSALLDAEPPILYSEYDPTFSEASMMGLLTNLADRELVHMIN
WAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLL
LDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVY
TFEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHM
SNKGMEHLYSMKCKNVVPLSDLLLEMLDAHRL
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5egv Predictive features of ligand-specific signaling through the estrogen receptor.
Resolution2.863 Å
Binding residue
(original residue number in PDB)
I358 K362 L372 Q375 V376 L379 D538 L539 E542 M543
Binding residue
(residue number reindexed from 1)
I49 K53 L63 Q66 V67 L70 D221 L222 E225 M226
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:5egv, PDBe:5egv, PDBj:5egv
PDBsum5egv
PubMed27107013
UniProtP03372|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)

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