Structure of PDB 5efn Chain B Binding Site BS01
Receptor Information
>5efn Chain B (length=357) Species:
7955
(Danio rerio) [
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PITGLVYDQRMMLHHNMWDSHHPELPQRISRIFSRHEELRLLSRCHRIPA
RLATEEELALCHSSKHISIIKSSEHMKPRDLNRLGDEYNSIFISNESYTC
ALLAAGSCFNSAQAILTGQVRNAVAIVRPPGHAAEKDTACGFCFFNTAAL
TARYAQSITRESLRVLIVDWDVHHGNGTQHIFEEDDSVLYISLHRYEDGA
FFPNSEDANYDKVGLGKGRGYNVNIPWNGGKMGDPEYMAAFHHLVMPIAR
EFAPELVLVSAGFDAARGDPLGGFQVTPEGYAHLTHQLMSLAAGRVLIIL
EGGYNLTSISESMSMCTSMLLGDSPPSLDHLTPLKTSATVSINNVLRAHA
PFWSSLR
Ligand information
>5efn Chain F (length=3) Species:
9606
(Homo sapiens) [
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RGG
Receptor-Ligand Complex Structure
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PDB
5efn
Histone deacetylase 6 structure and molecular basis of catalysis and inhibition.
Resolution
1.804 Å
Binding residue
(original residue number in PDB)
N530 S531 P571 H573 G582 F583 D612 H614 F643 Y745
Binding residue
(residue number reindexed from 1)
N89 S90 P130 H132 G141 F142 D171 H173 F202 Y304
Enzymatic activity
Enzyme Commision number
3.5.1.98
: histone deacetylase.
External links
PDB
RCSB:5efn
,
PDBe:5efn
,
PDBj:5efn
PDBsum
5efn
PubMed
27454933
UniProt
F8W4B7
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