Structure of PDB 5e14 Chain B Binding Site BS01

Receptor Information
>5e14 Chain B (length=237) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADREL
VHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLF
APNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILL
NSGVYTFKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLL
ILSHIRHMSNKGMEHLYSMNVVPLSDLLLEMLDAHRL
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB5e14 Predictive features of ligand-specific signaling through the estrogen receptor.
Resolution2.22 Å
Binding residue
(original residue number in PDB)
I358 K362 V376 L379 E380 D538 L539 E542
Binding residue
(residue number reindexed from 1)
I54 K58 V72 L75 E76 D226 L227 E230
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:5e14, PDBe:5e14, PDBj:5e14
PDBsum5e14
PubMed27107013
UniProtP03372|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)

[Back to BioLiP]